Randomized clinical trials

Tepe G, Schnorr B, Albrecht T, Brechtel K, Claussen CD, Scheller B, Speck U, Zeller T.
Angioplasty of femoral-popliteal arteries with drug-coated balloons: 5-years follow-up of the THUNDER trial.
J Am Coll Cardiol Intv 2015;8:102–108 [PubMed]

Werk M, Albrecht T, Meyer R-D, Ahmed MN, Behne A, Dietz U, Eschenbach G, Hartmann H, Lange C, Schnorr B, Stiepani H, Biondi Zoccai G, Lopez Hänninen E.
Paclitaxel-coated balloons reduce restenosis after femoro- popliteal angioplasty. Evidence from the randomized PACIFIER trial.
Circ Cardiovasc Interv. 2012;5: [PubMed]

Scheller B, Clever YP, Kelsch B, Hehrlein C, Bocksch W, Rutsch W, Haghi D, Dietz U, Speck U, Böhm M, Cremers B.
Long-term follow-up after treatment of coronary in-stent restenosis with a paclitaxel coated balloon catheter.
JACC Cardiovasc Interv. 2012; 5: 323-330 [PubMed]

Tepe G, Zeller T, Albrecht T, Heller S, Schwarzwälder U, Beregi JP, Claussen CD, Oldenburg A, Scheller B, Speck U.
Local delivery of paclitaxel to inhibit restenosis during angioplasty of the leg.
N Engl J Med. 2008;358:689-699. [PubMed]

Scheller B, Hehrlein C, Bocksch W, Rutsch W, Haghi D, Dietz U, Böhm M, Speck U.
Treatment of coronary in-stent restenosis with a paclitaxel-coated balloon catheter.
N Engl J Med. 2006;355:2113-2124. [PubMed]

Contributions to product development

Clever YP, Peters D, Calisse J, Bettink S, Berg M-C, Sperling C, Stoever M, Cremers B, Kelsch B, Bohm M, Speck U, Scheller B.
Novel Sirolimus–coated balloon catheter. In vivo evaluation in a porcine coronary model.
Circ Cardiovasc Interv. 2016;9:e003543. DOI: 10.1161/CIRCINTERVENTIONS.115.003543 [PubMed]

Kelsch B, Scheller B, Biedermann M, Clever YP, Schaffner S, Mahnkopf D, Speck U, Cremers B.
Dose-response to paclitaxel-coated balloon catheters in the porcine coronary overstretch and stent implantation model.
Invest Radiol. 2011;46:255-263 [PubMed]

Cremers B, Speck U, Kaufels N, Mahnkopf D, Kühler M, Böhm M, Scheller B.
Drug-eluting balloon: Very short-term exposure and overlapping.
Thromb Haemost. 2009;101:201-206 [PubMed]


Cremers B, Toner JL, Schwartz LB, von Oepen R, Speck U, Kaufels N, Clever YP, Mahnkopf D, Böhm M, Scheller B.
Inhibition of neointimal hyperplasia with a novel Zotarolimus coated balloon catheter.
Clin Res Cardiol. 2012; 101: 469-476 [PubMed]

Speck U, Cremers B, Kelsch B, Biedermann M, Clever YP, Schaffner S, Mahnkopf D, Hanisch U, Böhm M, Scheller B.
Does pharmacokinetics explain persistent restenosis inhibition by a single dose of paclitaxel?
Circ Cardiovasc Interv. 2012;5:392-400 [PubMed]

Cremers B, Kelsch B, Clever YP, Hattangadi N, Mahnkopf D, Speck U, Taupitz M, Scheller B.
Inhibition of neointimal proliferation after bare metal stent implantation with low-pressure drug delivery using a paclitaxel-coated balloon in porcine coronary arteries.
Clin Res Cardiol. 2012; 101: 385-391 [PubMed]

Early experimental studies

Speck U, Scheller B, Abramjuk C, Breitwieser C, Dobberstein J, Böhm M, Hamm B.
Neointima inhibition: comparison of effectiveness of non-stent-based local drug delivery and a drug-eluting stent in porcine coronary arteries.
Radiology. 2006;240:411-418 [PubMed]

Scheller B, Speck U, Abramjuk C, Bernhardt U, Böhm M, Nickenig G.
Paclitaxel balloon coating - a novel method for prevention and therapy of restenosis.
Circulation. 2004; 110: 810-814 [PubMed]

Scheller B, Speck U, Schmitt A, Böhm M, Nickenig G.
Addition of Paclitaxel to contrast media prevents restenosis after coronary stent implantation.
J Am Coll Cardiol 2003; 42: 1415-1420 [PubMed]

Scheller B, Speck U, Romeike B, Schmitt A, Sovak M, Böhm M, Stoll HP.
Contrast media as carriers for local drug delivery. Successful inhibition of neointimal proliferation in the porcine coronary stent model.
Eur Heart 2003; 24: 1462-1467 [PubMed]

Clauss W., Scheller B., Schmitt A., Sovak M., Speck U.
No difference among modern contrast media’s effect on neointimal proliferation and restenosis following coronary stenting in pigs.
Invest Radiol 2003; 38: 743-749 [PubMed]

Speck U., Scheller B., Puls R., Stroszczynski C.
Paradigms and perspectives in contrast media research. Harry Fischer Memorial Lecture.
Acad Radiol 2002;9 (suppl 2): S 392-397 [PubMed]

Scheller B, Speck U, Schmitt A, Clauss W, Sovak M, Böhm M, Stoll HP.
Acute cardiac tolerance of current contrast media and the new taxane protaxel using iopromide as carrier during porcine coronary angiography and stenting.
Invest Radiol 2002; 37: 29-34 [PubMed]